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Amphotericin B is an antifungal medication primarily used to treat serious fungal infections. It is derived from the bacterium Streptomyces nodosus and works by binding to ergosterol, a key component of fungal cell membranes, leading to cell death. This makes it effective against a variety of fungal pathogens, including Candida and Aspergillus species. Amphotericin B is typically used in hospital settings for patients with compromised immune systems or severe infections.
| Chemical formula | C47H73N7O17 |
| Molecular weight | 925.17 g/mol |
| Form | Lyophilized powder |
| Solubility | Soluble in dimethyl sulfoxide and slightly soluble in water |
| Storage conditions | Store at 2-8°C, protected from light |
When selecting Amphotericin B, buyers should consider the required purity levels and any specific grades that may be necessary for their applications. It is important to specify the desired packaging, such as bulk or smaller quantities, and to inquire about stability data and shelf life. Certifications such as Good Manufacturing Practices (GMP) may also be relevant, depending on the intended use.
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It is primarily used to treat serious fungal infections.
It is usually administered intravenously in a clinical setting.
Common side effects include fever, chills, and kidney toxicity.
Consider purity, packaging, and manufacturer certifications.
It is typically used in patients with severe infections or compromised immune systems.
It is effective against many fungi, but not all species are susceptible.