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Croscarmellose Sodium is a cross-linked polymer of carboxymethylcellulose, widely used as a pharmaceutical excipient. It functions primarily as a disintegrant, facilitating the breakdown of tablets and capsules in the digestive tract. This ensures that the active ingredients are released efficiently for absorption. Croscarmellose Sodium is known for its high swelling capacity and rapid disintegration properties, making it a preferred choice in various formulations.
| Chemical formula | C8H10NaO4 |
| Appearance | White to off-white powder |
| Solubility | Swellable in water |
| pH range | 6.0 to 8.0 |
| Moisture content | Typically less than 10% |
When choosing Croscarmellose Sodium, consider the specific application and formulation requirements. Buyers should specify the desired grade, as different grades may have varying disintegration properties. Additionally, it is important to inquire about the moisture content and pH range to ensure compatibility with other ingredients. Certifications such as USP or EP may also be relevant depending on regulatory requirements.
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It acts as a disintegrant in pharmaceutical formulations.
It is primarily used in pharmaceuticals, but some grades may be acceptable for food applications.
It offers rapid disintegration and high swelling capacity, often outperforming traditional disintegrants.
It should be stored in a cool, dry place, away from moisture and heat.
Yes, it can be used effectively in wet granulation processes.
It generally ranges from 20 to 100 microns.