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Irinotecan Hydrochloride is a potent chemotherapeutic agent used primarily in the treatment of colorectal cancer. It is a water-soluble salt derived from the alkaloid camptothecin and works by inhibiting the enzyme topoisomerase I, which is essential for DNA replication and repair. This mechanism leads to the disruption of cancer cell proliferation, making it effective in various cancer therapies.
| Chemical formula | C33H38N4O6S |
| Molecular weight | 588.74 g/mol |
| Purity | Typically ≥ 98% |
| Solubility | Soluble in water and organic solvents |
| Storage conditions | Store in a cool, dry place, away from light |
When selecting Irinotecan Hydrochloride, buyers should consider the required purity levels and any specific regulatory certifications needed for their applications. It is important to specify the desired quantity and packaging options, as well as any relevant stability data. Buyers may also inquire about the supplier's compliance with Good Manufacturing Practices (GMP) and other industry standards.
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It is primarily used in the treatment of colorectal cancer.
It is usually administered intravenously.
Common side effects include nausea, diarrhea, and fatigue.
It is often used in combination with other chemotherapy agents.
It should be stored in a cool, dry place, away from light.
Look for compliance with Good Manufacturing Practices (GMP) and relevant pharmacopoeial standards.