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Polyethylene Glycol 400 (PEG 400) is a water-soluble polymer that is widely used in the pharmaceutical industry as an excipient. It is synthesized from ethylene oxide and is known for its low viscosity and hygroscopic properties. PEG 400 serves as a carrier for active pharmaceutical ingredients, enhancing their solubility and bioavailability in various formulations.
| Molecular weight | Approx. 400 g/mol |
| Appearance | Clear, colorless to pale yellow liquid |
| Viscosity | Low viscosity, typically 20-30 mPa·s at 25°C |
| Solubility | Soluble in water and many organic solvents |
| Purity | Typically greater than 99% for pharmaceutical grade |
When selecting Polyethylene Glycol 400, consider the required purity level, as pharmaceutical-grade PEG 400 is essential for drug formulations. Specify the desired viscosity and any specific regulatory compliance or certifications needed for your application. Additionally, determine the quantity required, as bulk purchasing may offer cost advantages.
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It is primarily used as a solvent and carrier in pharmaceutical formulations.
Yes, PEG 400 is generally recognized as safe and is widely used in pharmaceutical applications.
Yes, PEG 400 is also used in food and cosmetic products as a carrier.
PEG 400 typically has a low viscosity of about 20-30 mPa·s at 25°C.
Store PEG 400 in a cool, dry place away from direct sunlight.
PEG 400 enhances the solubility and bioavailability of active ingredients.