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Spironolactone is a synthetic steroid that functions as a potassium-sparing diuretic and an anti-androgen. It is primarily used to treat conditions such as hypertension, heart failure, and edema by promoting the excretion of sodium while retaining potassium. The compound works by antagonizing the action of aldosterone, a hormone that regulates sodium and water balance in the body.
| Chemical formula | C24H32O4S |
| Molecular weight | 388.57 g/mol |
| Purity | Typically ≥ 98% |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in alcohol, slightly soluble in water |
When selecting spironolactone as a pharmaceutical raw material, buyers should consider the required purity levels and any specific regulatory standards applicable to their region. It is important to specify the desired quantity, as bulk orders may be subject to different pricing structures. Additionally, inquire about the supplier's certifications and quality assurance processes to ensure compliance with industry standards.
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Spironolactone is used to treat conditions like hypertension, heart failure, and edema.
It works by blocking aldosterone, leading to increased sodium excretion and potassium retention.
The typical purity is usually ≥ 98%.
It can be used long-term under medical supervision, especially for chronic conditions.
It is commonly available as a tablet or in compounded formulations.
Side effects may include hyperkalemia, gastrointestinal disturbances, and hormonal effects.